GHK-Cu

GHK-Cu is a copper-binding tripeptide composed of glycine, histidine, and lysine complexed with copper. It is used as a research compound for investigating copper-dependent signaling, extracellular matrix activity, cellular remodeling, and related biochemical pathways under controlled laboratory conditions.

Experimental work involving GHK-Cu has examined collagen-associated pathways, fibroblast activity, matrix metalloproteinases, oxidative-stress responses, angiogenesis-related signaling, and changes in gene expression.

This material is supplied exclusively for laboratory research and analytical applications.

Specifications

Product Classification: Research Use Only (RUO)
Compound: GHK-Cu (Copper Tripeptide-1)
Total Content: 100 mg per vial
Sequence: Gly-His-Lys-Cu
Form: Lyophilized research material
Packaging: Research vial
Purity: ≥99% (include only when confirmed by the applicable batch COA)
Intended Use: Laboratory research and analytical purposes only

Research Applications

GHK-Cu may be used in controlled laboratory models investigating:

• Copper-peptide interactions
• Extracellular matrix signaling
• Collagen-associated pathways
• Fibroblast activity
• Matrix metalloproteinases
• Cellular remodeling
• Oxidative-stress pathways
• Angiogenesis-associated signaling
• Gene-expression responses

Warning

FOR RESEARCH USE ONLY. NOT FOR HUMAN OR VETERINARY USE. NOT FOR HUMAN CONSUMPTION.

This product is intended solely for qualified laboratory research and analytical applications.

Scientific Report

Abstract

GHK-Cu is a copper-coordinating tripeptide used experimentally to investigate relationships between peptide-copper complexes and cellular signaling. Laboratory and preclinical studies have examined its interaction with extracellular matrix components, collagen-associated processes, fibroblast activity, metalloproteinases, angiogenesis-related signaling, oxidative-stress pathways, and gene-expression systems.

Mechanistic Pathways

Copper-Binding Activity

Copper coordination is a defining biochemical property of GHK-Cu. This characteristic makes the compound useful for experimental investigation of peptide-mediated copper interactions.

Research focus: Copper coordination and associated biochemical signaling.

Extracellular Matrix Activity

Experimental models have examined GHK-Cu in relation to collagen, glycosaminoglycans, matrix metalloproteinases, and other components associated with extracellular matrix turnover.

Research focus: Matrix signaling and remodeling pathways.

Cellular Signaling

GHK-Cu has been investigated in cellular models involving fibroblast activity, cellular migration, and other signaling responses.

Research focus: Cellular behavior under controlled experimental conditions.

Oxidative-Stress Pathways

Laboratory models have also investigated relationships between GHK-Cu and cellular responses to oxidative stress.

Research focus: Oxidative-stress and cellular-response signaling.

Research Profile

Compound: GHK-Cu
Classification: Copper-binding tripeptide
Primary Research Areas: Copper signaling, extracellular matrix biology, cellular signaling
Research Setting: Laboratory and preclinical models

Research Parameters

Experimental concentrations, exposure periods, controls, and assay conditions depend on the research model and endpoint being studied. Appropriate parameters should be established from validated experimental protocols and applicable scientific literature.

No instructions for human or veterinary use are provided.

Research Highlights

• Copper-peptide interactions
• Extracellular matrix models
• Collagen-associated signaling
• Fibroblast research
• Metalloproteinase activity
• Oxidative-stress pathways
• Angiogenesis-associated signaling
• Gene-expression studies

Conclusion

GHK-Cu is a laboratory research compound of interest for studying copper-peptide chemistry and its relationship with extracellular matrix and cellular signaling systems.